| Department of Theoretical and Applied Sciences (DiSTA) |
University of Insubria
Cultured hemocytes X. nematophila- FITC S. carpocapsae E. coli phagocytosis AMPs PAGE
| Lab Members|
Maurizio F. Brivio PhD
Head of Lab
Modulation of Innate Immunity in animal models.
Recent advances in understanding how some animal models eliminate pathogens and parasites
have confirmed the crucial role of innate immunity to protect them from infections.
Our research is focused on the interaction between humoral and cellular defence systems of insect
hosts before and after challenge with bacteria and parasitic nematodes.
In many cases the early interaction between host and foreign invaders involves surface compounds
of pathogens that play a role in the host immunoevasion or depression.
So, we investigate immune responses in animal models (particularly insects) to understand if and
how they are able to counteract microorganisms or parasites infection and at the same time, we study
the elusive strategies implemented by pathogens; besides, we are investigating the effects of priming
and immunomodulatory drugs on the host immune responses.
Particularly, we are studying:
· Cell-mediated responses, such as phagocytosis and encapsulation.
· The host immune responses are monitored in both naive and infected/parasitized insect larvae,
with or without priming or immunomodulatory drugs administration.
· Surface compounds from parasites and pathogenic bacteria involved in evasion and depression
· of host immunity.
Publications Members shots
Dept. of Theoretical and Applied Sciences (DiSTA) - University of Insubria - via J.H. Dunant 3. 21100 Varese (Italy)