Dr. Ester Papa was born in Varese (Italy) in 1977. She graduated cum Laude in Biology in 2001 with a thesis titled “Environmental fate of persistent organic pollutants: a QSAR approach” at the QSAR and Environmental Chemistry Research Unit of the University of Insubria (Varese, Italy) under the supervision of prof. Paola Gramatica.

In 2005, at the same university and still under the supervision of prof. Gramatica, she completed her PhD-thesis titled “QSAR approach to Persistent, Bioaccumulable, and Toxic (PBT) organic pollutants, sources of biodiversity stress”, obtaining a PhD in ''Analysis, Protection and Management of Biodiversity''.

During her PhD-studies she spent a total of six months working at the John Moores University (Liverpool, UK), in the QSAR and Modelling Group under the supervision of Dr. Mark T.D. Cronin, and at the Umeå university (Umeå , Sweden), in the Miljökemi research unit under the supervision of Dr. Patrik Andersson.

She is now working as a post doc researcher at the QSAR and Environmental Chemistry Research Unit in the department of structural and functional biology of the University of Insubria of Varese (Italy). Since her graduation she supervised eight students, Master of Science in Biological Sciences, and she takes part to the teaching activity with seminars for the Environmental Chemistry, Risk assessment and Ecotoxicology courses. During her current research she applies QSAR (Quantitative Structure-Activity Relationships) and multivariate analysis to different topics related to environmental pollution such as:

  • The environmental partitioning of pesticides

  • Atmospheric reactivity of Volatile Organic Compounds (VOCs)

  • Environmental fate of Persistent Organic compounds (POPs)

  • Bioconcentration of organic pollutants in aquatic organisms

  • Toxicity of organic pollutants to aquatic organisms

  • Screening and prioritization of Persistent, Bioaccumulative and Toxic compounds

  • (PBTs) and POPs for regulatory purposes

  • Synthesis and environmental fate of pharmaceuticals and endocrine disruptors

  She is the author or co-author of 26 publications in international scientific journals and she presented over 60 scientific contributions to national and international congresses in the field of environmental chemistry and QSAR (SETAC, MESAEP, QSAR, EuChEMS, SCI and SITE).

She has received the best poster presentation award at the 10th EuChEMS-DCE International Conference in Rimini (2005) with a poster entitled: “Organic pollutant uptake and bioconcentration in vegetation”.

She is a member of SETAC and of the Italian Chemistry Society (SCI) since 2001 and she is a referee for Chemosphere and for the Journal of Pharmaceutical and Biomedical Analysis.

Dr. Ester Papa publications on international Journals (2002-2007)

1)      P.Gramatica, E.Papa, Screening and ranking of POPs for Global Half-Life: a QSAR approach for prioritization, Environ. Sci. Technol., 2007, 41, 2833-2839.

2)      H. Liu, E. Papa, P. Gramatica, In silico Screening of Estrogen-Like Chemicals Based on Different Nonlinear Classification Models, Journal of Molecular Graphics and Modelling 2007, doi:10.1016/j.jmgm.2007.01.003 online.

3)      E. Papa, J. Fick, R. Lindberg, M. Johansson, P. Gramatica, P. L. Andersson. Multivariate chemical mapping of antibiotics and identification of structurally representative Substances. Environ. Sci. Technol., 2007, 41, 1653-1661.

4)      E.Papa, J.Dearden, P.Gramatica Linear QSAR regression models for the prediction of bioconcentration factors by physicochemical properties and structural theoretical molecular descriptors. Chemosphere, 2007, 67, 351-358.

5)   P. Gramatica, E. Giani, E. Papa Statistical external validation and consensus modeling: A QSPR case study for Koc prediction Journal of Molecular Graphics and Modelling 2007, 25, 755-766.

6)      P.Gramatica, P.Pilutti, E.Papa Approaches for externally validated QSAR modeling of Nitrated Polycyclic Aromatic Hydrocarbon mutagenicity SAR QSAR Environ. Res., 2007, Vol. 18 (1-2), 169-178.

7)      P. Gramatica, E. Papa, A. Marrochi, L.Minuti, A. Taticchi, QSAR Modelling of PAH Mutagenicity by Classification Methods based on Holistic Theoretical Molecular Descriptors, Ecotoxicology and Environmental Safety, 2007, 66, 353-361.

8)      H. Liu, E. Papa, P. Gramatica QSAR Prediction of Estrogen Activity for a Large Set of Diverse Chemicals under the Guidance of OECD Principles. Chemical Research in Toxicology, 2006, 19, 1540-1548.

9)      Nizzetto, L; Jones, KC; Gramatica, P; Papa, E; Cerabolini, B; Di Guardo, A. Accumulation of persistent organic pollutants in canopies of different forest types: Role of species composition and altitudinal-temperature gradient. Environmental Science and Technology, 2006, 40, 21, 6580-6586.

10)   Gramatica, P; Battaini, F; Giani, E; Papa, E; Jones, RJA; Preatoni, D; Cenci, RM. Analysis of mosses and soils for quantifying heavy metal concentrations in Sicily: A multivariate and spatial analytical approach. Environmental Science and Pollution Research, 2006, 13, 1, 28-36

11)   Banfi, S; Caruso, E; Buccafurni, L; Murano, R; Monti, E; Gariboldi, M; Papa, E; Gramatica, P. Comparison between 5,10,15,20-tetraaryl- and 5,15-diarylporphyrins as photosensitizers: Synthesis, photodynamic activity, and quantitative structure-activity relationship modeling, Journal of Medicinal Chemistry, 2006, 49, 11, 3293-3304

12)    Gramatica, P; Battaini, F; Giani, E; Papa, E; Jones, RJA; Cenci, RM. Multivariate analysis of heavy metal concentrations in soils and mosses of two North-Italy regions. Fresenius Environmental Bulletin, 2006, 15, 8, 731- 737

13)   E. Papa, F. Battaini and P. Gramatica Ranking of Esters’ Aquatic Toxicity modelled by QSAR.

Chemosphere 2005, Vol 58/5, 559-570. (IF: 2.297).

14)   P. Gramatica, P. Pilutti and E. Papa, Ranking of Phenols for Abiotic Oxidation in Aqueous Environment: a QSPR Approach. Annali di Chimica, 95, 2005, 199-209

15)   P. Gramatica and E. Papa An update of the BCF QSAR model based on theoretical molecular descriptors. QSAR and Combinatorial Science, 24, 2005, 953-960

16)   E. Papa, F. Villa and P.Gramatica Statistically validated QSARs, based on theoretical descriptors, for modeling aquatic toxicity of organic chemicals in Pimephales promelas (Fathead Minnow).J. Chem. Inf. Model., 45, 2005, 1256-1266.

17)   E. Papa, S. Castiglioni, P. Gramatica, V. Dukhovny, O. Kayumov and D. Calamari  Screening the leaching tendency of pesticides applied in Amu Darya Basin (Uzbekistan) Water Research , 38, 2004, 3485-3494.

18)   P. Gramatica, P. Pilutti and E. Papa Validated QSAR Prediction of OH Tropospheric degradability: splitting into training-test set and consensus modeling. J.Chem. Inf. Comp.Sci.. 44, 2004, 1794-1802.

19)   P. Gramatica, E. Papa and F. Battaini  Ranking and classification of non-ionic organic pesticides for environmental distribution: a QSAR approach. Int. J. Environ. Anal. Chem. 2004. 84 (1-3): 65-74.

20)   P. Gramatica, F. Battaini and E. Papa QSAR prediction of physico-chemical properties of esters. Fresenius Environmental Bulletin 13,  2004, 1258-1262.

21)   P. Gramatica, E. Papa and S. Pozzi Prediction of POP environmental Persistence and Long Range Transport by QSAR and Chemometric Approaches. Fresenius Environmental Bulletin 13,  2004, 1204-1209.

22)   P. Gramatica, P. Pilutti and E. Papa  A Tool for the Assessment of VOC Degradability by Tropospheric Oxidants Starting from Chemical Structure. Atmos. Environ. 2004, 38(36), 6167-6175.

23)   P. Gramatica, P. Pilutti and E. Papa. QSAR Prediction of Ozone Tropospheric Degradation  QSAR &Combinatorial Science, 22, 2003, 364-373.

24)   P. Gramatica and E. Papa QSAR Modeling of Bioconcentration Factor by Theoretical Molecular Descriptors QSAR &Combinatorial Science, 22, 2003, 374-385.

25)   P. Gramatica, P. Pilutti and E. Papa Predicting the NO3 Tropospheric Degradability of Organic Pollutants by Theoretical Molecular Descriptors. Atmos. Environ., 37 (22) , 2003, 3115-3124.

26) P. Gramatica, P. Pilutti and E. Papa. Ranking of Volatile Organic Compounds for Tropospheric Degradability by Oxidants: a QSPR Approach. SAR QSAR Environ. Res., 13, 2002, 743-753.