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She
graduated in Pure Chemistry in 1972 at the University of
Milan, where she carried out researches devoted to the
biosynthesis, structural elucidation, synthesis, and
biotransformation of organic natural products in the
Department of Organic and Industrial Chemistry till
1994.
Her present research field is in QSAR modelling of
environmental pollutants. She is author of more than one
hundred papers in international journals, peer reviewed
(about 60 in QSAR field), and more than two hundreds
presentations at meetings (mainly international).
EDUCATION
Graduation in Pure Chemistry (Organic Natural Compounds) cum
laude - 1972, University of Milan.
EMPLOYMENT
-Full
Professor of Environmental Chemistry and Cultural
Heritage, Faculty
of Sciences (Biology, Biotechnology, Natural Sciences
and Environmental Engineer courses) Insubria University-
present (since 2005)
-Associate
Professor of Organic Chemistry 1995 –2005, Faculty of Sciences (Biology,
Biotechnology, Natural Sciences courses) Insubria
University
-Researcher
in Organic Chemistry
1981- 1995 Department of Organic Chemistry, Milano University
(Associate Professor in 1987).
-Research
Contractor in Organic Chemistry 1975-1981 Department of Organic
Chemistry, Milano University
-Fellowshiper (Lincei Nat. Acad. and MIUR) 1972-1975 Department of Organic Chemistry, Milano University
Professional
Qualifications and Associations:
-
Member of the Italian
Chemical Society (SCI)
-
Member of the Managing Board
of the Environmental and Cultural Heritage Div. of
SCI
-
Member of the Managing Board
of the Interdivisional Group of Green Chemistry
(SCI)
-
Member of the Society of
Environmental Toxicology and Chemistry (SETAC).
-
Member of the Directive of
the SETAC-Italian Branch
-
Member of the QSAR and
Modeling Society
-
Member of the Mediterranean
Scientific Association of Environmental Protection
(MESAEP)
-
Member of the
InterUniversities Consortium on Biostructures and
Biosystems
-
Member of the OECD Expert Group on Quantitative Structure-Activity
Relationships (QSARs)
Membership
of Editorial Boards:
-
Guest Editor of Environmental
Science and Pollution Research 2006 (Special Issue and
Sections in memory of Prof. Davide Calamari)
-
Referee of many international scientific journals in
environmental field and chemical application of
computer science.
-
Scientific
responsible in 2 EU-Projects on mixture toxicity (BEAM
and PREDICT).
Recent Research interests:
Since 1994 PG has been working on
QSAR and chemometric methods’ applications to
environmentally relevant organic compounds. Her principal area of interest is the
QSAR modelling and prediction of physico-chemical
properties and biological activities of environmental
pollutants (PAHs, PCBs, pesticides, aromatic and aliphatic
organic compounds, etc.). Recent applications of these studies deal with tropospheric
oxidations of Volatile Organic Compounds (VOCs),
Persistent Organic Pollutants (POPs) long-range transport
and persistence, pesticide partition properties,
mutagenicity/carcinogenicity of PAHs/PACs,
Bioconcentration Factor (BCF) and Endocrine Disruptors
Chemicals (EDCs) modeling. The main field of interest is
relative to Persistent Bioaccumulative and Toxic (PBTs)
chemicals. An important aspect of the research
is the proposal of methods for the validation of QSAR
models.
She is working as QSAR expert for the European Joint
Research Centre (JRC-Ispra) and for OECD (Organization for
Economic Cooperation and Development) in the validation of
QSAR models for regulatory acceptance in the new European
policy of chemicals (REACH).
Teaching experience and appointments
The
teaching activity is devoted to various courses related to
the environmental pollution by chemicals for Biology (Environmental
Pollution and Ecotoxicology) and Engineering degrees, in
particular: Environmental Chemistry I and II, Risk
Assessment, Analytical Chemistry and Chemometrics,
Environmental Legislation and Certification, in addition
to the course of Organic Chemistry for Biology,
Biotechnology and Analysis and Protection of Natural
Resources.
Paola Gramatica is Coordinator of Environmental Pollution
and Ecotoxicology courses for the Degrees in Biology (undergradute
and graduate) and she represents the Faculty of Sciences
(Varese) in the International Relations Commission of the
University of Insubria.
Address:
QSAR
Research Unit in Environmental Chemistry and Ecotoxicology
Department of Structural and Functional Biology
Insubria
University
Via
J.H. Dunant 3
21100
Varese – Italy
Telephone:
+
39 0332 421573
Fax: +
39 0332 421554
e-mail:
paola.gramatica@uninsubria.it
web :
http://dipbsf.uninsubria.it/qsar/
; http://www.qsar.it
Personal
Information:
Married;
2 sons | 
