Log_CL in vitro, int (mL/h/10^6 cells)
08.58_InVitroHCL_HumanHep_AmineHydroxylation_b_rank2
QSAR PaDEL-Descriptor model for intrinsic in vitro clearance of heterogeneous chemicals measured in hepatocyte.
The in vitro intrinsic clearance represents the liver's ability to transform the substance 
independently of the blood flow and the availability of the substance.
The in vitro intrinsic clearance is defined as the ratio between the maximum speed of the reaction and the Michaelis constant.
Toxtree software has been used to predict the most likely reactions that can occur at Cytochrome P450 enzyme level. 
Amine hydroxylation has been identified as most probable reaction for the molecules within this training set.
