| Modifier and Type | Class and Description |
|---|---|
class |
CategoryBiodegradable
Class 1 (easily biodegradable chemical).
|
class |
CategoryPersistent
Class 2 (persistent chemical).
|
| Modifier and Type | Class and Description |
|---|---|
class |
CategoryCorrosiveEye
Assigned when compound is estimated to be corrosive to skin.
|
class |
CategoryCorrosiveSkin |
class |
CategoryModerateIrritation2Eye |
class |
CategoryNotCorrosive2Eye |
class |
CategoryNotCorrosive2Skin
Assigned when compound is estimated to be not corrosive to skin.
|
class |
CategoryNotCorrosive2SkinAndIrritating2Eye |
class |
CategoryNotCorrosive2SkinEye |
class |
CategoryNotCorrosive2SkinOrIrritating2Eye |
class |
CategoryNotIrritating2Eye
Assigned when compound is estimated to be not irritating to skin.
|
class |
CategoryNotIrritatingOrCorrosive2Eye
Assigned when compound is estimated to be not Irritating or corrosive to skin.
|
| Modifier and Type | Class and Description |
|---|---|
class |
micronucleusClass1 |
class |
micronucleusClass2 |
| Modifier and Type | Class and Description |
|---|---|
class |
CategoryMichaelAcceptor |
| Modifier and Type | Class and Description |
|---|---|
class |
CategoryCarcinogen |
class |
CategoryNoGenotoxicAlert |
class |
CategoryNoNongenotoxicAlert |
class |
CategoryNotCarcinogen |
class |
CategoryPositiveAlertGenotoxic |
class |
CategoryPositiveAlertNongenotoxic |
class |
MutantCategory |
| Modifier and Type | Class and Description |
|---|---|
class |
CategoryCorrosive
Assigned when compound is estimated to be corrosive to skin.
|
class |
CategoryIrritating
Assigned when compound is estimated to be irritating to skin.
|
class |
CategoryIrritatingOrCorrosive
Assigned when compound is estimated to be irritating or corrosive to skin.
|
class |
CategoryNotCorrosive
Assigned when compound is estimated to be not corrosive to skin.
|
class |
CategoryNotIrritating
Assigned when compound is estimated to be not irritating to skin.
|
class |
CategoryNotIrritatingOrCorrosive
Assigned when compound is estimated to be not Irritating or corrosive to skin.
|
class |
CategoryUnknown
Assigned when
SicretRules are not able to estimate skin irritation or corrosive potential. |
| Modifier and Type | Class and Description |
|---|---|
class |
AmesMutagenicityCategory |
class |
CategoryError |
class |
CategoryMutagenTA100 |
class |
CategoryNoAlertAmes |
class |
CategoryNonMutagen |
class |
CategoryPositiveAlertAmes |
class |
QSARApplicable |
| Modifier and Type | Class and Description |
|---|---|
class |
AcylTransferAlerts
Acyl transfer
|
class |
DNABindingCategory |
class |
MichaelAcceptors
Michael Acceptors
|
class |
NoAlerts
No alerts
|
class |
ShiffBaseAlerts
Shiff base
|
class |
SN1Alerts
Substrate has structural alerts for Nucleophilic Aromatic Substitution
|
class |
SN2Alerts
second order nucleophilic aliphatic substitution reaction
|
| Modifier and Type | Class and Description |
|---|---|
class |
FuncCat1 |
class |
FuncCat2 |
| Modifier and Type | Class and Description |
|---|---|
class |
NegligibleRisk |
class |
NotASafetyConcern
Substance would not be expected to be a safety concern
|
class |
RequireCompoundSpecificToxicityData |
| Modifier and Type | Field and Description |
|---|---|
protected DefaultCategory |
KroesRule8.category |
| Modifier and Type | Class and Description |
|---|---|
class |
CYP1A2 |
class |
CYP2A |
class |
CYP2B |
class |
CYP2C |
class |
CYP2D |
class |
CYP2E |
class |
CYP3A4 |
| Modifier and Type | Class and Description |
|---|---|
class |
CategoryAcetylcholinesteraseInhibitors |
class |
CategoryCentralNervousSystemSeizureAgents |
class |
CategoryElectrophileProelectrophileReactivity |
class |
CategoryNarcosis1
Assigned when compound is estimated to be corrosive to skin.
|
class |
CategoryNarcosis2 |
class |
CategoryNarcosis3 |
class |
CategoryOxidativePhosphorylationUncouplers |
| Modifier and Type | Class and Description |
|---|---|
class |
ProteinBindingCategory |
class |
SNArAlerts
Substrate has structural alerts for Nucleophilic Aromatic Substitution
|
| Modifier and Type | Class and Description |
|---|---|
class |
Found
Not found
|
class |
NotFound
Not found
|
| Modifier and Type | Class and Description |
|---|---|
class |
SkinSensitisationCategory |
| Modifier and Type | Class and Description |
|---|---|
class |
NoSites |
class |
SitesHigherRank |
class |
SitesRank1 |
class |
SitesRank2 |
class |
SitesRank3 |
| Modifier and Type | Class and Description |
|---|---|
class |
NonToxicCategory
A non toxic category
|
class |
ToxicCategory
A toxic category
|
| Modifier and Type | Class and Description |
|---|---|
class |
DefaultClass1 |
class |
DefaultClass2 |
| Modifier and Type | Class and Description |
|---|---|
class |
CramerClass1
A
DefaultCategory descendant, implementation of
Cramer class 1 (see CramerRules) |
class |
CramerClass2
A
DefaultCategory descendant, implementation of
Cramer class 2 (see CramerRules) |
class |
CramerClass3
A
DefaultCategory descendant, implementation of
Cramer class 3 (see CramerRules) |
| Modifier and Type | Class and Description |
|---|---|
class |
Class1BaselineToxicity
Class 1 (narcosis or baseline toxicity).
|
class |
Class2LessInertCompounds
Class 2 (less inert compounds).
|
class |
Class3UnspecificReactivity
Class 3 (unspecific reactivity).
|
class |
Class4SpecificMechanism
Class 4 (compounds and groups of compounds acting by a specific mechanism).
|
class |
Class5Unknown
Class 5 Not possible to classify according to these rules.
|
Copyright © 2004–2018 Ideaconsult Ltd. All rights reserved.